Raoul Daoust

Urgentologue Chercheur

Évaluation et traitement de la douleur aigue
Utilisation optimale de l'analgésie
Utilisation optimale des opioides

MD
CSPQ
MSc

1. Daoust R, Paquet J, Cournoyer A, Piette É, Morris J, Lessard J, Castonguay V, Williamson D, Chauny JM. Side effects from opioids used for acute pain after emergency department discharge. Am J Emerg Med. 2019 Jun 3.
2. Daoust R., OPUM project, Limiting Opioid Prescribing. JAMA. 2019 Jul 9;322(2):170-171
3. Daoust R, Paquet J, Gosselin S, Lavigne G, Cournoyer A, Piette E, Morris J, Castonguay V, Lessard J, Chauny JM. Opioid Use and Misuse Three Months After Emergency Department Visit for Acute Pain. Acad Emerg Med. 2019 Jul 18
4. Daoust R, Paquet J, Cournoyer A, Piette É, Morris J, Lessard J, Castonguay V, Lavigne G, Chauny JM. Acute Pain Resolution After an Emergency Department Visit: A 14-Day Trajectory Analysis. Ann Emerg Med. 2019 Aug; 74(2):224-232.
5. Daoust R, Paquet J, Cournoyer A, Piette É, Morris J, Gosselin S, Émond M, Lavigne G, Lee J, Chauny JM. Quantity of opioids consumed following an emergency department visit for acute pain: a Canadian prospective cohort study. BMJ Open. 2018 Sep 17;8(9):e022649
6. Daoust R, Paquet J, Moore L, Gosselin S, Gélinas C, Rouleau DM, Bérubé M, Morris J. Incidence and Risk Factors of Long-term Opioid Use in Elderly Trauma Patients. Ann Surg. 2018 Dec;268(6):985-991.
7. Daoust R, Paquet J, Moore L, Émond M, Gosselin S, Lavigne G, Choinière M, Boulanger A, Mac-Thiong JM, Chauny JM. Recent opioid use and fall-related injury among older patients with trauma. CMAJ. 2018 Apr 23;190(16)
8. Daoust R, Paquet J, Moore L, Émond M, Gosselin S, Lavigne G, Choinière M, Boulanger A, Mac-Thiong JM, Chauny JM. Early Factors Associated with the Development of Chronic Pain in Trauma Patients. Pain Res Manag. 2018 Jan 30;2018
9. Daoust R, Paquet J, Lavigne G, Piette É, Chauny JM. Impact of age, sex and route of administration on adverse events after opioid treatment in the emergency department: a retrospective study. Pain Res Manag. 2015 Jan-Feb;20(1):23-8

1. Combien prescrire d’opioïde au congé de l’urgence pour une douleur aiguë. ASMUQ annual meeting, Canada (2018).
2. Relationship Between Pain, Opioid Treatment, and Delirium in Emergency Department Elderly Patients. SAEM 2018 Annuel Meetings, United States
3. Opioid Use and Dependance Three Months After an Emergency Department
Visit for Acute Pain. SAEM 2018 Annuel Meeting, United States
4. Utilisation optimale de l’analgésie pour la douleur aiguë. Congrès journée interpôle Québec-Montréal 2018, Québec, Canada
5. Ketamine vs morphine for acute pain. Nouveautés et controverses 2017, Canada

Chercheur principal
Quantity of Opioids for Acute Pain and Limit Unused Medication (OPUM study),
Subvention, Fonctionnement
Est-ce que c'est un projet de recherche clinique?: Oui
Description du projet: The ultimate goal of this research program is to decrease opioid
misuse by lowering the quantity of unused medications. The primary objective of this
project is to determine the quantity of opioids consumed during the acute pain phase (2
weeks) by ED-discharged patients treated for an acute pain condition. The secondary
objectives are to inventory the quantity of opioids prescribed and unused after ED visits,
use of co-analgesics, pain intensity, and health services revisits during the 2-week followup.
Mise en application de la recherche: Our results will determine the quantity of opioids
consumed during the acute pain phase (2 weeks) to ED-discharged patients treated
for acute pain conditions. Our team members from relevant provincial and national
stakeholders and patient associations, our strong evidence, and our extensive knowledge
transfer strategy have the potential to impact Canadian physicians’ opioid prescription
practices. Consequently, fewer unused prescription opioids should lead to a substantial
decrease in the currently high rate of opioid misuse in Canada.
Sources de financement:
2018/10 - 2022/10 Instituts de Recherche en Santé du Canada (IRSC)
subvention projet
Montant total - 742 051 (Dollar canadien)

Co-chercheur
Connecting Emergency Departments with Community services to prevent mobility losses
in pre-frail & frail Seniors (CEDeComS), Subvention, Fonctionnement
Est-ce que c'est un projet de recherche clinique?: Oui
Description du projet: About 18% of independent people over 65 who are evaluated in
Emergency Departments for minor injuries (fractures, sprains) present some mobility
decline up to 3 to 6 months post-injury. People at risk of decline are prefrail or frail; this
condition could be explained by muscle proprieties loss. Exercise is a proven method
that can help limit frailty and allow to restore mobility. The aim of our study is to evaluate
whether a suitable exercise program of one hour, twice a week for 12 weeks will limit
functional losses & fragility in injured older adults after their emergency department visit.
Sources de financement:
2016/3 - 2020/3 Instituts de Recherche en Santé du Canada (IRSC)
subvention projet
Montant total - 1 643 676 (Dollar canadien)
Portion de financement reçu - 169 828 (Dollar canadien)

Co-chercheur
ED Ultrasonographic Regional Anesthesia to Prevent Incident Delirium in Hip Fracture
Patients (EDU_RAPID), Subvention, Fonctionnement
Est-ce que c'est un projet de recherche clinique?: Oui
Description du projet: For the first 6 -12 weeks of the trial, allpatients with a hip fracture
seen at one of our 6 participating hospitals inToronto,Kingston, Ottawa, Montreal and
Quebec City will receive standard ofcare narcotic analgesics. Then we willtrain physicians
4 at a time ever 6 weeks at each of the 6 centers until allparticipating physicians are
trained. The order in which physicians receivetraining will be randomized. This type
of randomized controlled trial is calleda step-wedge design. Randomization of order
of training isimportant because if only keen physicians with ultrasound training get
trainedearly, and reluctant physicians with no US experience are trained late, thiscould
bias our results. To further protect against such bias, we will stratifyrandomization
according to previous ultrasound training and experience.
BROUILLON
Dr Raoul Daoust
8
Sources de financement:
2015/7 - 2019/7 Instituts de Recherche en Santé du Canada (IRSC)
HS3 Recherche en interventions et en évaluation dans les services
de santé 3
Montant total - 561 326 (Dollar canadien)
Portion de financement reçu - 65 701 (Dollar canadien)

Chercheur principal
Incidence and identification of risk factors associated with the development of chronic pain
in emergency post-traumatic patients, Subvention, Fonctionnement
Est-ce que c'est un projet de recherche clinique?: Non
Description du projet: Objectives: 1) Establish the incidence, individualcharacteristics
and use/cost of health resources of trauma patients developingchronic pain and compared
them to patients not developing chronic pain. 2) Create and validate apredictive model
of chronic pain development for post-traumaticpatient from risk factors identified at
hospitaladmission. Methods: This project is a case-control study. Crossing 3 databases:
1) the “Régie del’Assurance Maladie du Québec” 2) “Banque de données ministériellessur
le Séjours Hospitaliers and the 3) “Banque de DonnéesMinistérielle du Registre des
Traumatismes du Quebec”governmentaldatabases, we will include all patients 18 years
and older admitted for injuryto any of the 57 adult trauma centers in the province of
Quebec between 2004and 2014. Injury subpopulations to be evaluated will include,
but will not be limitedto orthopedic injury, spinal cord injuries, traumatic brain injury,
andthoracic/abdominal injury.
Mise en application de la recherche: The first benefit of the project will be to provide
managers anddecision-makers a detailed picture of patients who will develop chronic
painfollowing injury: incidence and risk factors. Knowing the prevalence of chronicpain and
pain clinic consultation in trauma patients should also estimate theresources they need
and potential benefits of prevention in this population.Creating a predictive model that
identifies, at time of admission for trauma,the population at risk of developing chronic pain
will allow the testing ofpreventive approaches. In addition, it is likely that the dissemination
of ourresults stimulates the development of prevention programs and prospective followupof
this clientele, evaluation of the effectiveness of therapeutic approaches,their costbenefit
and especially improving the quality of life of post-traumapatients.
Sources de financement:
2016/4 - 2018/4 Fonds de recherche du Québec - Santé (FRQS)
consortium pour le développement de la recherche en traumatologie
volet 1
Montant total - 121 920 (Dollar canadien)

Co-chercheur
Incidence et mesure des impacts du délirium induit par l'urgence., Subvention,
Fonctionnement
Est-ce que c'est un projet de recherche clinique?: Oui
Description du projet: L'objectif principal de cette étude est de combler une lacune dans
les connaissances de base en ce qui concerne l'incidence, la gravité et les effets du
délirium induit dans le segment de la clientèle de 65 ans et plus qui vivent un séjour
prolongé à l’urgence (> 12 heures). Plus précisément, nous allons : A) Mesurer la
proportion d'incidence du délirium induit par l’urgence, B) évaluer et comparer l'incidence
du délirium à différents hôpitaux compte tenu du niveau d’implantation de leur «l'approche
adaptée». C) Mesurer la durée de séjour des patients souffrant d’un épisode de délirium
induit, la comparer aux patients sans délirium et mesurer les impacts potentiels sur le
surpeuplement des urgences participantes. D) Évaluer le potentiel prédicteur de variables
clinico-administratives sur les épisodes de délirium induit par l’urgence. E) Mesurer et
comparer la proportion de retour nonplanifié à l’urgence et le déclin fonctionnel dans les
60 jours suivants le congé de l'hôpital.
Sources de financement:
2015/4 - 2017/4 Fonds de recherche du Québec - Santé (FRQS)
Recherches sur l'urgence et le continuum des soins - Volet 1
Montant total - 270 000 (Dollar canadien)
Portion de financement reçu - 20 736 (Dollar canadien)