Razvan Diaconescu

Réponse immunitaire dirigée contre le cancer
Thérapies cellulaires anti-néoplasiques

2001-2004 Fellowship en therapie cellulaire (Fred Hutchinson Cancer Research Center, Seattle, USA)
1999-2001 Residence en Hématologie (Université Laval, Québec)
1996-1999 Résidence en Médecine Interne (Université Laval, Québec)
1992-1996 MD Faculté de Médecine (Université Laval, Québec)
1990-1992 BSc Biologie (Université d'Ottawa)
1988-1990 Faculté de Médecine (Bucarest, Roumanie)

Treatment delays in non-small cell lung cancer and their prognostic implications.
Diaconescu R, Lafond C, Whittom R.
J Thorac Oncol. 2011 Jul;6(7):1254-9.
PMID: 21610526

What role is there for antithymocyte globulin in allogeneic nonmyeloablative canine hematopoietic cell transplantation?
Diaconescu R, Little MT, Leisenring W, Yunusov M, Hogan WJ, Sorror ML, Baron F, Storb R.
Biol Blood Marrow Transplant. 2005 May;11(5):335-44.
PMID: 15846286

Allogeneic hematopoietic cell transplantation: from experimental biology to clinical care.
Diaconescu R, Storb R.
J Cancer Res Clin Oncol. 2005 Jan;131(1):1-13. Review.
PMID: 15565456

Morbidity and mortality with nonmyeloablative compared with myeloablative conditioning before hematopoietic cell transplantation from HLA-matched related donors.
Diaconescu R, Flowers CR, Storer B, Sorror ML, Maris MB, Maloney DG, Sandmaier BM, Storb R.
Blood. 2004 Sep 1;104(5):1550-8.
PMID: 15150081

Analysis of the Genomic Landscape in ALK+ NSCLC Patients Identifies Novel Aberrations Associated with Clinical Outcomes.
Couëtoux du Tertre M, Marques M, Tremblay L, Bouchard N, Diaconescu R, Blais N, Couture C, Pelsser V, Wang H, Higenell V, Izzi L, Gambaro K, Hoffert C, Srivastava A, Spatz A, Rousseau C, McNamara S, Cohen V, Batist G, Agulnik J.
Mol Cancer Ther. 2019 Sep;18(9):1628-1636.
PMID: 31243098

Adoptive immunotherapy against allogeneic kidney grafts in dogs with stable hematopoietic trichimerism.
Graves SS, Hogan WJ, Kuhr C, Diaconescu R, Harkey M, Sale GE, Stone B, Georges GE, Storb R.
Biol Blood Marrow Transplant. 2008 Nov;14(11):1201-8.
PMID: 18940673

Intensified postgrafting immunosuppression failed to assure long-term engraftment of dog leukocyte antigen-identical canine marrow grafts after 1 gray total body irradiation.
Sorror ML, Leisenring W, Mielcarek M, Baron F, Diaconescu R, Hogan WJ, Graves SS, Storb R.
Transplantation. 2008 Apr 15;85(7):1023-9.
PMID: 18408584

Stable trichimerism after marrow grafting from 2 DLA-identical canine donors and nonmyeloablative conditioning.
Graves SS, Hogan W, Kuhr CS, Diaconescu R, Harkey MA, Georges GE, Sale GE, Zellmer E, Baran SW, Jochum C, Stone B, Storb R.
Blood. 2007 Jul 1;110(1):418-23.
PMID: 17369487

Prognostic relevance of 'early-onset' graft-versus-host disease following non-myeloablative haematopoietic cell transplantation.
Mielcarek M, Burroughs L, Leisenring W, Diaconescu R, Martin PJ, Sandmaier BM, Maloney DG, Maris MB, Chauncey TR, Shizuru JA, Blume KG, Hegenbart U, Niederwieser D, Forman S, Bruno B, Woolfrey A, Storb R.
Br J Haematol. 2005 May;129(3):381-91.
PMID: 15842663

Graft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning.
Baron F, Maris MB, Sandmaier BM, Storer BE, Sorror M, Diaconescu R, Woolfrey AE, Chauncey TR, Flowers ME, Mielcarek M, Maloney DG, Storb R.
J Clin Oncol. 2005 Mar 20;23(9):1993-2003.
PMID: 15774790

Lessened severe graft-versus-host after "minitransplantations".
Sorror M, Maris M, Diaconescu R, Storb R.
Blood. 2005 Mar 15;105(6):2614.
PMID: 15746087

Comparison of ARF after myeloablative and nonmyeloablative hematopoietic cell transplantation.
Parikh CR, Schrier RW, Storer B, Diaconescu R, Sorror ML, Maris MB, Maloney DG, McSweeney P, Storb R, Sandmaier BM.
Am J Kidney Dis. 2005 Mar;45(3):502-9.
PMID: 15754272

Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities.
Sorror ML, Maris MB, Storer B, Sandmaier BM, Diaconescu R, Flowers C, Maloney DG, Storb R.
Blood. 2004 Aug 15;104(4):961-8. Epub 2004 Apr 27.
PMID: 15113759

Postgrafting immunosuppression with sirolimus and cyclosporine facilitates stable mixed hematopoietic chimerism in dogs given sublethal total body irradiation before marrow transplantation from DLA-identical littermates.
Hogan WJ, Little MT, Zellmer E, Friedetzky A, Diaconescu R, Gisburne S, Lee R, Kuhr C, Storb R.
Biol Blood Marrow Transplant. 2003 Aug;9(8):489-95.
PMID: 12931117